Luciano G. Nardo, MD MRCOG

Mr Nardo trained in Italy, London and Manchester until he was appointed as NHS consultant in gynaecology and reproductive medicine at the CMFT University Hospitals, St Mary's Hospital, Manchester where he worked until August 2011. He is a Royal College of Obstetricians and Gynaecologists (RCOG) member and accredited subspecialist in reproductive medicine and surgery. He has vast experience in advanced laparoscopic (keyhole) surgery for the treatment of endometriosis, adhesions, fibroids, ovarian cysts, tubal surgery and other benign gynaecological conditions. He performs complex laparoscopic procedures such as myomectomy, hysterectomy and reversal of sterilisation as day case procedures in private hospitals in Manchester and London. Mr Nardo has clinical and academic interests in pelvic pain, menstrual disorders, infertility, assisted conception, gynaecological endocrinology and hysteroscopic management of intrauterine abnormalities (including fibroids, septa and severe adhesions, like in Asherman's Syndrome). He has expertise in gynaecological ultrasound scan and management of early pregnancy problems, including recurrent miscarriage, and he runs dedicated clinics.

Mr Nardo is a member of the RCOG, and an associate member of many international learned societies, including the European Society of Human Reproduction and Embryology (ESHRE), the American Society for Reproductive Medicine (ASRM) and the British Fertility Society (BFS). He is past chair of the training committee of the BFS and serves on the education committee of the International Federation of Fertility Societies (IFFS). Mr Nardo is former chairman of the Mediterranean Society for Reproductive Medicine (MSRM) and is actively involved in promoting gynaecology education and training opportunities in the UK and abroad. He is a preceptor for the BSF special skill modules in Pelvic Ultrasound, Embryo Transfer, Management of the Infertile Couple and Assisted Conception. Mr Nardo is regular organiser of many national and international courses and meetings in the field of gynaecology, infertility, assisted conception, gynaecological endocrinology, ultrasound and advanced laparoscopic surgery. In particular, he works very closely with the ESHRE Special Interest Group in Reproductive Surgery and the RCOG.

Mr Nardo has a strong research programme both in the UK and abroad focusing on polycystic ovary syndrome (PCOS), endometriosis, ovarian reserve, ovarian stimulation, repeated IVF failures and mechanisms of embryo implantation. He is co-investigator of some international multicentre research trials. He has published widely on many aspects of gynaecology, reproductive medicine and surgery, and has written several textbook chapters and edited journals' supplements. Mr Nardo has been an invited speaker to over 80 conferences worldwide and has held several visiting positions in Europe and the Intercontinental region. He is an ad-hoc reviewer for many international scientific journals and publishers. Currently is member of the editorial board of the peer-reviewed journal Reproductive BioMedicine Online and is Section Editor for Endometriosis and Reproductive Surgery. Mr Nardo is a recognised opinion leader by patients' organisation, scientific societies, academic institutions, non-profit organisations, media and pharmaceutical companies.

List of Mr Nardo's Publications:

Anti-Mullerian hormone tailored protocols improve outcomes whilst reducing adverse effects and costs of IVF. Yates AP, Lim HYN, Pemberton PW, Rustamov O, Smith A, Roberts SA, Nardo LG. Hum. Reprod., 2011; 26:2353-2362.

Age-related normograms of serum anti-müllerian hormone levels in a population of infertile women: a multicenter study. Almog B, Shehata F, Suissa S, Holzer H, Shalom-Paz E, La Marca A, Muttukrishna S, Blazar A, Hackett R, Nelson SM, Cunha-Filho JS, Eldar-Geva T, Margalioth EJ, Raine-Fenning N, Jayaprakasan K, McIlveen M, Wunder D, Freour T, Nardo LG, Balasch J, Peñarrubia J, Smeenk J, Gnoth C, Godehardt E, Lee TH, Lee MS, Levin I, Gamzu R, Tulandi T. Fertil. Steril., 2011; 95:2359-2363.

Measured dehydroepiandrosterone sulphate positively influences testosterone measurements in unextracted female serum: comparison of 2 immunoassays with testosterone measured by LC-MS. Benton SC, Nuttall M, Nardo L, Laing I. Clin. Chem., 2011; 57:1074-1075.

Update in endometriosis and IVF. Gryparis I, Nardo LG. Minerva Ginecol., 2011; 63:571-576.

Live birth rate in fresh and frozen embryo transfer cycles in women with endometriosis. Mohamed AM, Chouliaras S, Jones CJ, Nardo LG. Eur. J. Obstet. Gynecol. Reprod. Biol., 2011; 156:177-180.

The reproducibility of serum AMH in subfertile women: within and between patient variability. Rustamov O, Pemberton PW, Roberts SA, Smith A, Yates AP, Patchava S, Nardo LG. Fertil. Steril., 2011; 95:1185-1187.

Failed IVF cycles and the risk of subsequent preeclampsia or fetal growth restriction: a case-control exploratory study. Tsoumpou I, Mohamed AM, Tower C, Roberts SA, Nardo LG. Fertil. Steril., 2011; 95:973-978.

Conventional ovarian stimulation no longer exists: welcome to the age of iCOS. Nardo LG, Fleming R, Howels C, Bosch E, Hamamah S, Ubaldi F, Hugues JN, Balen A, Nelson SM. RBM Online, 2011; 23:141-148.

Evidence-based management of endometrioma. Gelbaya TA, Nardo LG. RBM Online, 2011; 23:15-24.

Optimizing hormone therapy for future reproductive performance in women with premature ovarian failure. Gelbaya T, Vitthala S, Nardo L, Seif M. Gynecol. Endocrinol., 2011; 27:1-7.

Management of endometrioma prior to IVF: compliance with ESHRE guidelines. Gelbaya TA, Gordts S, D'Hooghe TM, Gergolet M, Nardo LG. RBM Online, 2010; 21:325-330.

The use of anti-Müllerian hormone and antral follicle count to predict the potential of oocytes and embryos. Majumder K, Gelbaya TA, Laing I, Nardo LG. Eur. J. Obstet. Gynecol. Reprod. Biol., 2010; 150:166-170.

Single nucleotide polymorphisms in the FSH receptor gene and ovarian performance: future role in IVF. Mohiyiddeen L, Nardo LG. Hum. Fertil., 2010; 13:72-78.

Growth hormone for in vitro fertilization. Duffy JM, Ahmad G, Mohiyiddeen L, Nardo LG, Watson A. Cochrane Database Syst Rev 2010; 1:CD000099.

Acupuncture and herbal medicine in in vitro fertilisation: a review of the evidence for clinical practice. Cheong Y, Nardo LG, Rutherford T, Ledger W. Hum. Fertil., 2010; 13:3-12.

Altered glycosylation in peri-implantation phase endometrium in women with stages III and IV endometriosis. Miller DL, Jones CJP, Aplin JD, Nardo LG. Hum. Reprod., 2010; 25:406-411.

Early stages of implantation as revealed by an in vitro model. Singh H, Nardo L, Kimber SJ, Aplin JD. Reproduction, 2010; 139:905-914.

Optimal dose of hCG for final oocyte maturation in IVF cycles: absence of evidence? Tsoumpou I, Muglu J, Gelbaya T, Nardo LG. RBM Online, 2009; 19:52-58.

Managing the complications associated with assisted reproductive technologies. Patchava S, Gelbaya TA, Nardo LG. Minerva Ginecol., 2009; 61:347-355.

The relationship between AMH, androgens, insulin resistance and basal ovarian follicular status in non-obese subfertile women with and without PCOS. Nardo LG, Yates AP, Roberts SA, Pemberton P, Laing I. Hum. Reprod., 2009; 24:2917-2923.

The likelihood of live birth and multiple birth after single versus double embryo transfer at the cleavage stage: a systematic review and meta-analysis. Gelbaya TA, Tsoumpou I, Nardo LG. Fertil. Steril., 2010; 94:936-945.

Eutopic endometrium from women with endometriosis shows altered ultrastructure and glycosylation compared to that from healthy controls - a pilot observational study. Jones CJP, Inuwa IM, Nardo LG, Litta P, Fazleabas AT. Reprod. Science, 2009; 16:559-572.

How can we reliably predict ovarian reserve? Mohiyiddeen L, Gelbaya TA, Nardo LG. MEFS Journal, 2009; 14: 1-8.

Medical adjuncts in IVF: evidence for clinical practice. Nardo LG, Granne I, Stewart J. Hum. Fertil., 2009; 12:1-13.

Peritoneal ectopic lesions from women with endometriosis show abnormalities in progesterone-dependent glycan expression. Jones CJ, Nardo LG, Litta P, Fazleabas AT. Fertil. Steril., 2009; 91:1608-1610.

The effect of surgical treatment for endometrioma on in-vitro fertilization outcomes: a systematic review and meta-analysis. Tsoumpou I, Kyrgiou M, Gelbaya TA, Nardo LG. Fertil. Steril., 2009; 92:75-87.

Circulating basal anti-Müllerian hormone levels as predictor of ovarian response in women undergoing ovarian stimulation for IVF. Nardo LG, Gelbaya TA, Wilkinson H, Roberts SA, Yates A, Pemberton P, Laing I. Fertil. Steril., 2009; 92:1586-1593.

Ultrastructure of ectopic peritoneal lesions from women with endometriosis, including observations on the contribution of coelomic mesothelium. Jones CJP, Nardo LG, Litta P, Fazleabas AT. Reprod. Science, 2009; 16:43-55.

The risk of monozygotic twinning after assisted reproduction technology: a systematic review and meta-analysis. Vitthala S, Gelbaya TA, Brison DR, Fitzgerald CT, Nardo LG. Hum. Reprod. Update, 2009; 15:45-55.

Polycystic ovary syndrome: pathophysiology, molecular aspects and clinical implications. Nardo LG, Patchava S, Laing I. Panminerva Med., 2008; 50:267-278.

Low grade inflammation, as evidenced by basal high sensitivity CRP, is not correlated to outcome measures in IVF. Robinson S, Pemberton P, Laing I, Nardo LG. J. Assist. Reprod. Genet, 2008; 25:383-388.

Stimulated intrauterine insemination (SIUI) and donor insemination (DI) as first line management for a selected subfertile population: the Manchester experience. Vitthala S, Gelbaya TA, Hunter H, Roberts SA, Nardo LG. J. Assist. Reprod. Genet., 2008; 25:431-436.

Implantation, clinical pregnancy and miscarriage rates after introduction of ultrasound guided embryo transfer. Rubina Ali C, Khashan AS, Horne G, Fitzgerald CT, Nardo LG. RBM Online, 2008; 17:88-93.

Evidence-based approach for the use of ultrasound in the management of polycystic ovary syndrome. Nardo LG, Gelbaya TA. Minerva Ginecol., 2008; 60:83-89.

The use of estradiol for luteal phase support in IVF/ICSI cycles: a systematic review and meta-analysis. Gelbaya TA, Kyrgiou M, Tsompou I, Nardo LG. Fertil. Steril., 2008; 90:2116-2125.

Proximal tubal disease: the place for tubal cannulation. Das S, Nardo LG, Seif MW. RBM Online, 2007; 15:383-388.

Anti-Mullerian hormone levels and antral follicle count in women enrolled in in vitro fertilization cycles: relationship to lifestyle factors, chronological age and reproductive history. Nardo LG, Christodoulou D, Gould D, Roberts SA, Fitzgerald CT, Laing I. Gynecol. Endocrinol., 2007; 24:1-8.

Low-dose aspirin for in-vitro fertilization: a systematic review and meta-analysis. Gelbaya TA, Kyrgiou M, Li TC, Stern C, Nardo LG. Hum. Reprod. Update, 2007; 13:357-364.

Ultrasonography in Polycystic Ovary Syndrome: an update. Nardo LG, Buckett WM, Orio F Jr. J. Reprod. Med., 2007; 52:390-396.

The optimal length of "coasting protocol" in women at risk of ovarian hyperstimulation syndrome undergoing in-vitro fertilization. Nardo LG, Horne G, Gelbaya TA, Cheema P, Fitzgerald CT, Pease EHE, Brison DR, Lieberman BA. Hum. Fertil., 2006; 9:175-180.

Progesterone supplementation to prevent recurrent miscarriage and to reduce implantation failure in ART cycles. Nardo LG, Sallam HN. RBM Online, 2006; 13:47-57.

Reproductive outcome after laparoscopic treatment of minimal and mild endometriosis using Helica Thermal Coagulator. Nardo LG, Moustafa M, Beynon DWG. Eur. J. Obstet. Gynecol. Reprod. Biol., 2006; 126:264-267.

Ovarian response to gonadotropins after laparoscopic salpingectomy or the division of fallopian tubes for hydrosalpinges. Gelbaya TA, Nardo LG, Fitzgerald CT, Horne G, Brison D, Lieberman BA. Fertil. Steril., 2006; 85:1464-1468.

Cryopreserved-thawed embryo transfer in natural or down-regulated hormonally controlled cycles: a retrospective study. Gelbaya TA, Nardo LG, Hunter HR, Fitzgerald CT, Horne G, Brison D, Pease EHE, Lieberman BA. Fertil. Steril., 2006; 85:603-609.

Customised foetal growth chart: a systematic review. Gelbaya T, Nardo LG. J. Obstet. Gynecol., 2005; 25:445-450.

Vascular endothelial growth factor expression in the endometrium during the menstrual cycle, implantation window and early pregnancy. Nardo LG. Curr. Opin. Obstet. Gynecol., 2005; 17:419-423.

Serum luteinizing hormone, follicle-stimulating hormone and oestradiol pattern in women undergoing pituitary suppression with different GnRH-analogue protocols for assisted reproduction. Manna C, Rahman A, Sbracia M, Pappalardo S, Mohamed EI, Linder R, Nardo LG. Gynecol. Endocrinol., 2005; 20:188-194.

Laparoscopic Helica treatment for pelvic pain associated with minimal and mild endometriosis. Nardo LG, Moustafa M, Beynon DWG. Fertil. Steril., 2005; 83:735-738.

Effect of a single dose mifepristone on expression of pinopodes in the endometrial surface in mice. Huang D, Nardo LG, Huang G, Lu F, Liu Y. Acta Pharmacol Sinica, 2005; 26:212-219.

The increase of leukocyte as a new putative marker of low-grade chronic inflammation and early cardiovascular risk in polycystic ovary syndrome. Orio F Jr, Palomba S, Cascella T, Di Biase S, Manguso F, Tauchmanova L, Nardo LG, Labella D, Savastano S, Russo T, Zullo F, Colao A, Lombardi G. J Clin. Endocrinol. Metab., 2005; 90:2-5.

Management of anovulatory infertility associated with PCOS: tamoxifen citrate an effective alternative compound to clomiphene citrate. Nardo LG. Gynecol. Endocrinol., 2004; 19:235-238.

Is Plasminogen Activator Inhibitor-1 (PAI-1) a cardiovascular risk factor in young women with polycystic ovary syndrome? Orio F Jr, Palomba S, Cascella T, Tauchmanovà L, Nardo LG, Di Biase S, Labella D, Russo T, Savastano S, Zullo F, Colao A, Lombardi G. RBM Online, 2004; 9:505-510.

Metformin administration versus laparoscopic ovarian diathermy in clomiphene citrate-resistant women with polycystic ovary syndrome: a prospective parallel randomized double-blind placebo-controlled trial. Palomba S, Orio F Jr, Nardo LG, Falbo A, Russo T, Corea D, Doldo P, Lombardi G, Colao A, Zullo F. J Clin. Endocrinol. Metab., 2004; 89:4801-4809.

Effect of ovarian stimulation on plasma lipid and apolipoprotein levels in a population of infertile women undergoing IVF-ET. Brizzi P, Dessole S, Tonolo G, Capobianco G, Milia L, Puddu L, Nardo LG. RBM Online, 2003; 7:309-312.

Persistent unilocular ovarian cysts in a general population of post-menopausal women. Is there a place for expectant management? Nardo LG, Kroon N, Reginald PW. Obstet. Gynecol., 2003; 102:589-593.

Synchronous expression of pinopodes and αVβ3 and α4β1 integrins in the endometrial surface epithelium of normally menstruated women during the implantation window. Nardo LG, Nikas G, Makrigiannakis A, Sinatra F, Nardo F. J. Reprod. Med., 2003; 48:355-361.

Determination of the best-fitting ultrasound formulaic method for ovarian volume measurement in polycystic ovary syndrome. Nardo LG, Buckett WM, Khullar V. Fertil. Steril., 2003; 79:632-633.

Molecules in blastocyst implantation: role of matrix metalloproteinases, cytokines and growth factors. Nardo LG, Nikas G, Makrigiannakis A. J. Reprod. Med., 2003; 48:137-147.

Expression of αVβ3 and α4β1 integrins throughout the putative window of implantation. Nardo LG, Bartoloni G, Di Mercurio T, Nardo F. Acta Obstet. Gynecol. Scand., 2002; 81:753-758.

Three dimensional (3D) assessment of ultrasound features in women with clomiphene citrate-resistant polycystic ovary syndrome: ovarian stromal volume does not correlate with biochemical indices. Nardo LG, Buckett WM, White D, Digesu AG, Franks S, Khullar V. Hum. Reprod., 2002; 17:1052-1055.

Pinopodes expression during human implantation. Nardo LG, Sabatini L, Rai R, Nardo F. Eur. J. Obstet. Gynecol. Reprod. Biol., 2002; 101:105-109.

High serum luteinizing hormone and testosterone concentrations do not predict pregnancy outcome in women with recurrent miscarriage. Nardo LG, Rai R, Backos M, El-Gaddal S, Regan L. Fertil. Steril., 2002; 77:348-352.

CO2 laser vaporization as primary therapy for HPV lesions. A prospective observational study. Savoca S, Nardo LG, Rosano TF, D'Agosta S, Nardo F. Acta Obstet. Gynecol. Scand., 2001; 80:1121-1124.

Concentrations of insulin-like growth factor (IGF)-I and IGF binding protein-3 in the follicular fluid of women undergoing ovarian hyperstimulation with different gonadotropin preparations. Nardo LG, Longo G, Burrello N, Bellanca SA, D'Agata R, Nardo F, Calogero AE. Gynecol. Endocrinol., 2001; 15:413-420.

Endometrial lesions after Tamoxifen therapy in breast cancer women. Maugeri G, Nardo LG, Campione C, Nardo F. Breast J., 2001; 7:240-244.

Metformin therapy in the management of polycystic ovary syndrome: endocrine, metabolic and reproductive effects. Nardo LG, Rai R. Gynecol. Endocrinol., 2001; 15:373-380.

Influence of anthropometric parameters on bone mineral density: correlations with age and sex. Savoca S, Nardo LG, Pignatello R, Messina K, D'Agosta S. Minerva Ginecol., 2001; 53:77-85.

Efficacy of recombinant follicle stimulating hormone versus urinary follicle stimulating hormone in in-vitro fertilization: a prospective, randomized, assessor-blind study. Nardo LG, Bellanca SA, Messina K, Nardo F. It. J. Gynaecol. Obstet., 2000; 2:49-53.